Week 6 NFL odds have been released and professional and amateur bettors are locking in their top picks. The Patriots opened as 3.5-point home favorites against the undefeated Chiefs on “Sunday Night Football” and the over-under for that game has already seen significant movement, rising from 57.5 to 59.5 as bettors anticipate fireworks from Patrick Mahomes and Tom Brady. Elsewhere on the NFL odds board, the Bengals are 2.5-point favorites at home against the Steelers, down a half-point from the opener, in what could be Pittsburgh’s final game without running back Le’Veon Bell. With so many NFL lines and spreads to choose from, be sure to check out the Week 6 NFL picks and predictions from SportsLine’s advanced computer model.
SportsLine’s proprietary computer model went 176-80 last season and beat over 95 percent of CBS Office Pool players in 2016 and ’17. It also performed better than 98 percent of experts tracked by NFLPickWatch.com during that span. Additionally, it went 48-34 on A-rated picks against the spread last season, and $100 bettors who have followed it the past two seasons are up nearly $4,000.
It went a blistering 10-5 straight up in a wild Week 5, including calling the Jets‘ outright upset of the Broncos. It also recommended the Bills (+6) against the spread and on the money line (+230) against the Titans. The model is now on an impressive 58-40 run on all of its top-rated picks and anyone who has followed it is way, way up.
Now it has simulated every snap 10,000 times and its Week 6 NFL picks are in.
One of the Week 6 NFL picks the model is all over: The Texans (-8.5) cover at home against the Bills.
The Bills have been one of the most up-and-down teams in the league. They shocked the Vikings and Titans as underdogs, but have also been blown out by the Ravens, Chargers and Packers by a combined 77 points.
The model sees another setback for Buffalo and projects Texans quarterback Deshaun Watson to account for over 300 yards of total offense Sunday. The Texans pick up their third consecutive win and cover in almost 55 percent of simulations.
Another one of the top Week 6 NFL picks from the model: The Rams (-7) continue their march toward a 2019 Super Bowl berth with another win and cover, this time against the Broncos.
Denver’s defense will try to slow a Rams offense that’s No. 1 in the league in total yardage (468.4 yards per game) and second in scoring (34.6 points per game). The model, however, is calling for more of the same from L.A. Todd Gurley goes off for over 120 yards from scrimmage, while Jared Goff pushes for 300 more through the air. The Rams cover the spread in almost 55 percent of simulations, while the over (52.5) hits over half the time as well.
The model also has a strong selection for “Sunday Night Football” between the Patriots and Chiefs, and is calling for a team with Super Bowl aspirations to get absolutely stunned on the road by an underdog.
What NFL picks can you make with confidence in Week 6? And what Super Bowl contender goes down hard? Check out the latest NFL odds below and then visit SportsLine to see which NFL teams are winning more than 50 percent of simulations, all from the model that has beaten 98 percent of experts over the past two years.
Philadelphia Eagles at New York Giants (+3, 44)
Seattle Seahawks vs. Oakland Raiders (+3, 48)
Los Angeles Chargers at Cleveland Browns (+1, 44.5)
Carolina Panthers at Washington Redskins (-2)
Indianapolis Colts at New York Jets (-2.5, 45)
Pittsburgh Steelers at Cincinnati Bengals (-2.5, 53)
Arizona Cardinals at Minnesota Vikings (-10.5, 43)
Chicago Bears at Miami Dolphins (+3, 42)
Buffalo Bills at Houston Texans (-8.5)
Tampa Bay Buccaneers at Atlanta Falcons (-3.5, 57.5)
Los Angeles Rams at Denver Broncos (+7, 52.5)
Jacksonville Jaguars at Dallas Cowboys (+3, 40.5)
Baltimore Ravens at Tennessee Titans (+3, 41)
Kansas City Chiefs at New England Patriots (-3.5, 59.5)
San Francisco 49ers at Green Bay Packers (-9.5, 46.5)