The Week 14 NFL schedule features a matchup of 10-2 teams in the Big Easy, an AFC heavyweight clash in Foxborough, and an NFC West showdown in Los Angeles. 49ers vs. Saints, Chiefs vs. Patriots, and Seahawks vs. Rams highlight a dizzying 16-game slate and mean plenty of tough decisions for your NFL office pool picks. Will the 49ers be winded after their bruising battle in Baltimore? Will New England solve its offensive woes against a mediocre Kansas City defense? Will the Rams, in a desperation spot at home, avenge their one-point loss in Seattle from Week 5? And which NFL confidence pool picks should you enter? Fans everywhere will be making NFL predictions on these games as well as the entire schedule. Before you make your own NFL picks, look at the Week 14 NFL football pool picks from SportsLine’s proven model.

This model, which simulates every NFL game 10,000 times, has ranked in the Top 10 in straight-up NFL picks on NFLPickWatch for three years running. Last season, it beat more than 96 percent of CBS Sports office pool players. 

Now the model has simulated the entire Week 14 NFL schedule 10,000 times and generated its optimal NFL pick’em plays. Go to SportsLine to see them. 

We can tell you the model likes the Saints to get past San Francisco and move into the NFC’s No. 1 seed. The 49ers thrive on running the ball, but New Orleans hasn’t allowed a 100-yard rusher in 41 straight games.

Playing before their raucous home fans, the Saints will make Niners quarterback Jimmy Garoppolo uncomfortable. New Orleans had an amazing 41 QB pressures in its Thanksgiving win in Atlanta, and the Saints are tied for fourth in the league with 40 sacks. The model has New Orleans winning in 59 percent of simulations. Book the Saints over the 49ers as part of your Week 14 NFL office pool picks.

The model also has made the call on Chiefs vs. Patriots, Titans vs. Raiders, Ravens vs. Bills, Seahawks vs. Rams and every other NFL Week 14 game. In fact, the model says one public darling goes down hard. You can only see all of the model’s NFL pool picks at SportsLine. 

So who should you pick in every Week 14 NFL game? And which public darling goes down hard? Visit SportsLine now to get optimal NFL office pool picks, all from the advanced computer model that has ranked in the Top 10 on straight-up picks three years running.