Week 2 of the NFL season features huge rivalry matchups and teams looking to redeem themselves from Week 1 disappointment. NFL odds are already posted as sportsbooks react to their first look at the regular season. Even with uncertainty surrounding Aaron Rodgers‘ knee, the Packers opened as one-point favorites against the Vikings. The Steelers are favored by 5.5 against the Chiefs, while the Patriots are two-point favorites against the Jaguars in a game that has already seen plenty of line movement. With NFL odds constantly changing and major storylines unfolding in Week 2, you’ll want to see the NFL picks and predictions from SportsLine’s advanced computer model.

This proprietary computer model went 176-80 last season and beat over 95 percent of CBS Office Pool players in 2016 and 2017. It also performed better than 98 percent of experts tracked by NFLPickWatch.com during that span. Additionally, it went 48-34 on A-rated picks against the spread last season, and $100 bettors who followed it the past two seasons are up nearly $4,000.

It finished Week 1 strong, nailing three of its final four picks, including backing the Jets (+281) on the money line in their 48-17 upset of the Lions on Monday night.

Now it has simulated every snap of Week 2 of the 2018 NFL season 10,000 times and its Week 2 NFL picks are in.

One Week 2 NFL pick the model likes: The Eagles (-3) knock off the Buccaneers on the road.

Nick Foles continues to fill in for Carson Wentz and the model says he pushes for 300 yards and two touchdowns. The Bucs get 263 yards from Ryan Fitzpatrick, who was impressive in place of Jameis Winston (suspension) in Week 1, but the Eagles win straight up 62 percent of the time and cover in well over half of simulations. Back the under (44) as well because that hits over 60 percent of the time.

Another one of the top Week 2 NFL picks, according to the model: The Redskins (-5.5) cover at home against the Colts.

The new backfield of Alex Smith and Adrian Peterson was impressive for Washington in a 24-6 victory in Week 1 at Arizona, and the model is calling for big numbers from both again against a Colts defense that gave up 34 points to the Bengals on Sunday.

Smith goes for just under 300 yards through the air as the Redskins win this one straight up 65 percent of the time and cover in almost 55 percent of simulations.

The model also has a strong pick you need to see for the huge AFC Championship Game rematch between the Patriots and Jaguars, and is calling for a top Super Bowl contender to get shocked on the road by a huge underdog.

What NFL picks can you make with confidence in Week 2? Check out the latest NFL odds below and then visit SportsLine to see which NFL teams are winning more than 50 percent of simulations, all from the model that has beaten 98 percent of experts over the past two years.

Baltimore Ravens at Cincinnati Bengals (PK, 44)

Cleveland Browns at New Orleans Saints (-8, 50)

Indianapolis Colts at Washington Redskins (-5.5, 45.5)

Minnesota Vikings at Green Bay Packers (-1, 46.5)

Los Angeles Chargers at Buffalo Bills (+7, 43)

Kansas City Chiefs at Pittsburgh Steelers (-5.5, 53)
Philadelphia Eagles at Tampa Bay Buccaneers (+3, 44)
Carolina Panthers at Atlanta Falcons (-5, 44)
Miami Dolphins at New York Jets (+1)
Arizona Cardinals at Los Angeles Rams (-10)
Detroit Lions at San Francisco 49ers (-3)
New England Patriots at Jacksonville Jaguars (+2, 45)
Oakland Raiders at Denver Broncos (-4.5)
New York Giants at Dallas Cowboys (-3, 42)